Improving Media & Buffer Preparation
Automated Media & Buffer Management with Precise Flow Meters and Bubble Detectors
Accurate flow and volume measurement is crucial in media and buffer preparation and delivery for both upstream and downstream processes, e.g., in cell culture media preparation, and buffer preparation for chromatography and filtration. By implementing high accuracy non-contact flow meters, the flow rate can be monitored in real-time and the volume dispensing can be precisely controlled to enable automated processes resulting in higher product quality and increased process efficiency.
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Improving Process Control with Real-Time Data
Buffers play a significant role in biopharmaceutical manufacturing. Precise buffer management is essential to ensure process consistency, compliance, and cost efficiency. In upstream processes, buffers are commonly used to improve pH and other process parameters to obtain the desired product quality according to the defined critical quality attributes. In downstream processes, they help to meet the defined purification criteria, e.g., to stabilize proteins.
Non-contact clamp-on flow meters can significantly enhance media and buffer management, improving efficiency and quality in processes such as media preparation, chromatography, and filtration. Their accuracy, contamination-free operation, and cost-effectiveness make them a valuable tool in GMP biopharmaceutical manufacturing.
Clamp-on flow meters enable real-time monitoring and control of liquid flow rates without the need for physical weighing. They provide highly accurate volume measurements and ensure accurate dosing of media and buffer. By integrating flow meters into automated systems, bioprocesses can achieve greater consistency, reduce manual intervention and increase operational efficiency. Replacing traditional scales with flow sensor-based automation minimizes errors, improves scalability and optimizes material usage - a preferred choice for advanced bioprocess applications.

Benefit from Real-Time Flow Measurement and Air Bubble Detection
Ultrasonic flow meters are crucial for buffer preparation and management in the bioprocessing industry. Integrated in automation systems, non-contact flow meters help to control consistent and accurate buffer delivery and reduce variability and human error.
High accuracy flow meters improve process control, data connectivity and predictive analytics, ensuring compliance with defined CQAs (critical quality attributes) while optimizing QbD (quality by design) strategies.
Your Benefits
- Enhanced Accuracy:
Ultrasonic technology ensures accurate flow measurement, which is critical for buffer composition and product quality. - Contamination Prevention:
Clamp-on flow meters eliminate the risk of microbes and cross-contamination by measuring from the outside through the wall of the tubing. - Lower Maintenance Costs:
Non-contact measurement is free of wear and tear, significantly reducing downtime and operating costs.
Benefit from our flow meters and air bubble detectors!
More Information about Ultrasonic Flow Meters
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